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Complexes of Ghrelin GHS-R1a, GHS-R1b, and Dopamine D(1) Receptors Localized in the Ventral Tegmental Area as Main Mediators of the Dopaminergic Effects of Ghrelin

Ghrelin receptor, also known as growth hormone secretagogue receptor (GHS-R1a), is coexpressed with its truncated isoform GHS-R1b, which does not bind ghrelin or signal, but oligomerizes with GHS-R1a, exerting a complex modulatory role that depends on its relative expression. D(1) dopamine receptor...

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Detalles Bibliográficos
Autores principales: Navarro, Gemma, Rea, William, Quiroz, César, Moreno, Estefanía, Gomez, Devan, Wenthur, Cody J., Casadó, Vicent, Leggio, Lorenzo, Hearing, Matthew C., Ferré, Sergi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824505/
https://www.ncbi.nlm.nih.gov/pubmed/34876469
http://dx.doi.org/10.1523/JNEUROSCI.1151-21.2021