Safety and immunogenicity of two recombinant DNA COVID-19 vaccines containing the coding regions of the spike or spike and nucleocapsid proteins: an interim analysis of two open-label, non-randomised, phase 1 trials in healthy adults

BACKGROUND: We assessed the safety and immunogenicity of two recombinant DNA vaccines for COVID-19: GX-19 containing plasmid DNA encoding the SARS-CoV-2 spike protein, and GX-19N containing plasmid DNA encoding the SARS-CoV-2 receptor-binding domain (RBD) foldon, nucleocapsid protein, and plasmid DN...

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Detalles Bibliográficos
Autores principales: Ahn, Jin Young, Lee, Jeongsoo, Suh, You Suk, Song, Young Goo, Choi, Yoon-Jeong, Lee, Kyoung Hwa, Seo, Sang Hwan, Song, Manki, Oh, Jong-Won, Kim, Minwoo, Seo, Han Young, Kwak, Jeong-Eun, Youn, Jin Won, Woo, Jung Won, Shin, Eui-Cheol, Sung, Young Chul, Park, Su-Hyung, Choi, Jun Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824525/
https://www.ncbi.nlm.nih.gov/pubmed/35156068
http://dx.doi.org/10.1016/S2666-5247(21)00358-X

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824525/
https://www.ncbi.nlm.nih.gov/pubmed/35156068
http://dx.doi.org/10.1016/S2666-5247(21)00358-X

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