Cargando…

HspB1 Overexpression Improves Life Span and Stress Resistance in an Invertebrate Model

To explore the role of the small heat shock protein beta 1 (HspB1, also known as Hsp25 in rodents and Hsp27 in humans) in longevity, we created a Caenorhabiditis elegans model with a high level of ubiquitous expression of the naked mole-rat HspB1 protein. The worms showed increased life span under m...

Descripción completa

Detalles Bibliográficos
Autores principales: Alexander, Courtney Carroll, Munkáscy, Erin, Tillmon, Haven, Fraker, Tamara, Scheirer, Jessica, Holstein, Deborah, Lozano, Damian, Khan, Maruf, Gidalevitz, Tali, Lechleiter, James D, Fisher, Alfred L, Zare, Habil, Rodriguez, Karl A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824566/
https://www.ncbi.nlm.nih.gov/pubmed/34610126
http://dx.doi.org/10.1093/gerona/glab296