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HspB1 Overexpression Improves Life Span and Stress Resistance in an Invertebrate Model
To explore the role of the small heat shock protein beta 1 (HspB1, also known as Hsp25 in rodents and Hsp27 in humans) in longevity, we created a Caenorhabiditis elegans model with a high level of ubiquitous expression of the naked mole-rat HspB1 protein. The worms showed increased life span under m...
Autores principales: | Alexander, Courtney Carroll, Munkáscy, Erin, Tillmon, Haven, Fraker, Tamara, Scheirer, Jessica, Holstein, Deborah, Lozano, Damian, Khan, Maruf, Gidalevitz, Tali, Lechleiter, James D, Fisher, Alfred L, Zare, Habil, Rodriguez, Karl A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824566/ https://www.ncbi.nlm.nih.gov/pubmed/34610126 http://dx.doi.org/10.1093/gerona/glab296 |
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