Structure-based discovery of selective CYP(17)A(1) inhibitors for Castration-resistant prostate cancer treatment

Prostate cancer (PCa) is the most common malignancy found in men and the second leading cause of cancer-related death worldwide. Castration-resistant PCa (CRPC) is defined by PCa cells that stop responding to hormone therapy. Cytochrome P450 17α-hydroxylase/17,20-lyase (CYP17A1) plays a critical rol...

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Detalles Bibliográficos
Autores principales: Omoboyowa, Damilola A, Balogun, Toheeb A, Saibu, Oluwatosin A, Chukwudozie, Onyeka S, Alausa, Abdullahi, Olubode, Samuel O, Aborode, Abdullahi T, Batiha, Gaber E, Bodun, Damilola S, Musa, Sekinat O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Methods Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824735/
https://www.ncbi.nlm.nih.gov/pubmed/35146123
http://dx.doi.org/10.1093/biomethods/bpab026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824735/
https://www.ncbi.nlm.nih.gov/pubmed/35146123
http://dx.doi.org/10.1093/biomethods/bpab026

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