The m(6)A RNA methyltransferase METTL3/METTL14 promotes leukemogenesis through the mdm2/p53 pathway in acute myeloid leukemia

N6-methyladenosine (m(6)A) is the most abundant internal modification in mammalian mRNA and recent studies have highlighted the importance of m(6)A levels in tumor development. In this study, we investigated the expression of methyltransferase-like 3 (METTL3) and 14 (METTL14), components of the RNA...

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Detalles Bibliográficos
Autores principales: Sang, Lina, Wu, Xia, Yan, Tianyou, Naren, Duolan, Liu, Xiaoyan, Zheng, Xue, Zhang, Nanchen, Wang, Huifang, Li, Yarong, Gong, Yuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824895/
https://www.ncbi.nlm.nih.gov/pubmed/35154467
http://dx.doi.org/10.7150/jca.60381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824895/
https://www.ncbi.nlm.nih.gov/pubmed/35154467
http://dx.doi.org/10.7150/jca.60381

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