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Targeted inhibition of ACLY expression to reverse the resistance of sorafenib in hepatocellular carcinoma

Resistance to sorafenib has been documented in hepatocellular carcinoma (HCC) patients. We investigated: (i) the correlation between adenosine triphosphate citrate lyase (ACLY) expression and sorafenib resistance in HCC; and (ii) if targeted inhibition could reverse sorafenib resistance. Samples of...

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Detalles Bibliográficos
Autores principales: Sun, Hong, Wang, Fengchao, Huang, Yongqiang, Wang, Jin, Zhang, Lunjun, Shen, Yong, Lin, Chao, Guo, Pu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824901/
https://www.ncbi.nlm.nih.gov/pubmed/35154461
http://dx.doi.org/10.7150/jca.52778