Using continuous directed evolution to improve enzymes for plant applications

Continuous directed evolution of enzymes and other proteins in microbial hosts is capable of outperforming classical directed evolution by executing hypermutation and selection concurrently in vivo, at scale, with minimal manual input. Provided that a target enzyme’s activity can be coupled to growt...

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Detalles Bibliográficos
Autores principales: García-García, Jorge D, Van Gelder, Kristen, Joshi, Jaya, Bathe, Ulschan, Leong, Bryan J, Bruner, Steven D, Liu, Chang C, Hanson, Andrew D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Regular Issue Content
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825276/
https://www.ncbi.nlm.nih.gov/pubmed/34718794
http://dx.doi.org/10.1093/plphys/kiab500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825276/
https://www.ncbi.nlm.nih.gov/pubmed/34718794
http://dx.doi.org/10.1093/plphys/kiab500

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