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Spatial structure governs the mode of tumour evolution

Characterizing the mode—the way, manner or pattern—of evolution in tumours is important for clinical forecasting and optimizing cancer treatment. Sequencing studies have inferred various modes, including branching, punctuated and neutral evolution, but it is unclear why a particular pattern predomin...

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Detalles Bibliográficos
Autores principales: Noble, Robert, Burri, Dominik, Le Sueur, Cécile, Lemant, Jeanne, Viossat, Yannick, Kather, Jakob Nikolas, Beerenwinkel, Niko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825284/
https://www.ncbi.nlm.nih.gov/pubmed/34949822
http://dx.doi.org/10.1038/s41559-021-01615-9