Multimodal profiling of the transcriptional regulatory landscape of the developing mouse cortex identifies Neurog2 as a key epigenome remodeler

How multiple epigenetic layers and transcription factors (TFs) interact to facilitate brain development is largely unknown. Here, to systematically map the regulatory landscape of neural differentiation in the mouse neocortex, we profiled gene expression and chromatin accessibility in single cells a...

Descripción completa

Detalles Bibliográficos
Autores principales: Noack, Florian, Vangelisti, Silvia, Raffl, Gerald, Carido, Madalena, Diwakar, Jeisimhan, Chong, Faye, Bonev, Boyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825286/
https://www.ncbi.nlm.nih.gov/pubmed/35132236
http://dx.doi.org/10.1038/s41593-021-01002-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825286/
https://www.ncbi.nlm.nih.gov/pubmed/35132236
http://dx.doi.org/10.1038/s41593-021-01002-4

Ejemplares similares