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Phenethyl Isothiocyanate Enhances the Cytotoxic Effects of PARP Inhibitors in High-Grade Serous Ovarian Cancer Cells

While PARP inhibitor (PARPi) therapies have shown promising results in the treatment of high-grade serous ovarian cancer (HGSOC) harboring homologous recombination deficiencies, primary resistance to PARPi frequently occurs and even initial responders may eventually become resistant. Therefore, the...

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Detalles Bibliográficos
Autores principales: Jia, Yaxun, Wang, Min, Sang, Xiaolin, Liu, Pixu, Gao, Jingchun, Jiang, Kui, Cheng, Hailing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825372/
https://www.ncbi.nlm.nih.gov/pubmed/35155204
http://dx.doi.org/10.3389/fonc.2021.812264