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Complete Protection Against Yersinia pestis in BALB/c Mouse Model Elicited by Immunization With Inhalable Formulations of rF1-V10 Fusion Protein via Aerosolized Intratracheal Inoculation

Pneumonic plague, caused by Yersinia pestis, is an infectious disease with high mortality rates unless treated early with antibiotics. Currently, no FDA-approved vaccine against plague is available for human use. The capsular antigen F1, the low-calcium-response V antigen (LcrV), and the recombinant...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Song, Xiaolin, Zhai, Lina, Guo, Jianshu, Zheng, Xinying, Zhang, Lili, Lv, Meng, Hu, Lingfei, Zhou, Dongsheng, Xiong, Xiaolu, Yang, Wenhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825376/
https://www.ncbi.nlm.nih.gov/pubmed/35154110
http://dx.doi.org/10.3389/fimmu.2022.793382