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Complete Protection Against Yersinia pestis in BALB/c Mouse Model Elicited by Immunization With Inhalable Formulations of rF1-V10 Fusion Protein via Aerosolized Intratracheal Inoculation
Pneumonic plague, caused by Yersinia pestis, is an infectious disease with high mortality rates unless treated early with antibiotics. Currently, no FDA-approved vaccine against plague is available for human use. The capsular antigen F1, the low-calcium-response V antigen (LcrV), and the recombinant...
Autores principales: | Zhang, Wei, Song, Xiaolin, Zhai, Lina, Guo, Jianshu, Zheng, Xinying, Zhang, Lili, Lv, Meng, Hu, Lingfei, Zhou, Dongsheng, Xiong, Xiaolu, Yang, Wenhui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825376/ https://www.ncbi.nlm.nih.gov/pubmed/35154110 http://dx.doi.org/10.3389/fimmu.2022.793382 |
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