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Extracellular citrate and metabolic adaptations of cancer cells

It is well established that cancer cells acquire energy via the Warburg effect and oxidative phosphorylation. Citrate is considered to play a crucial role in cancer metabolism by virtue of its production in the reverse Krebs cycle from glutamine. Here, we review the evidence that extracellular citra...

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Detalles Bibliográficos
Autores principales: Parkinson, E. Kenneth, Adamski, Jerzy, Zahn, Grit, Gaumann, Andreas, Flores-Borja, Fabian, Ziegler, Christine, Mycielska, Maria E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825388/
https://www.ncbi.nlm.nih.gov/pubmed/34932167
http://dx.doi.org/10.1007/s10555-021-10007-1