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Transcript Expression Profiles and MicroRNA Regulation Indicate an Upregulation of Processes Linked to Oxidative Stress, DNA Repair, Cell Death, and Inflammation in Type 1 Diabetes Mellitus Patients

Type 1 diabetes (T1D) arises from autoimmune-mediated destruction of insulin-producing β-cells leading to impaired insulin secretion and hyperglycemia. T1D is accompanied by DNA damage, oxidative stress, and inflammation, although there is still scarce information about the oxidative stress response...

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Detalles Bibliográficos
Autores principales: Takahashi, Paula, Xavier, Danilo J., Lima, Jessica E. B. F., Evangelista, Adriane F., Collares, Cristhianna V. A., Foss-Freitas, Maria C., Rassi, Diane M., Donadi, Eduardo A., Passos, Geraldo A., Sakamoto-Hojo, Elza T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825437/
https://www.ncbi.nlm.nih.gov/pubmed/35155683
http://dx.doi.org/10.1155/2022/3511329