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Transcript Expression Profiles and MicroRNA Regulation Indicate an Upregulation of Processes Linked to Oxidative Stress, DNA Repair, Cell Death, and Inflammation in Type 1 Diabetes Mellitus Patients
Type 1 diabetes (T1D) arises from autoimmune-mediated destruction of insulin-producing β-cells leading to impaired insulin secretion and hyperglycemia. T1D is accompanied by DNA damage, oxidative stress, and inflammation, although there is still scarce information about the oxidative stress response...
Autores principales: | Takahashi, Paula, Xavier, Danilo J., Lima, Jessica E. B. F., Evangelista, Adriane F., Collares, Cristhianna V. A., Foss-Freitas, Maria C., Rassi, Diane M., Donadi, Eduardo A., Passos, Geraldo A., Sakamoto-Hojo, Elza T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825437/ https://www.ncbi.nlm.nih.gov/pubmed/35155683 http://dx.doi.org/10.1155/2022/3511329 |
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