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Mechanisms of sex determination and X-chromosome dosage compensation
Abnormalities in chromosome number have the potential to disrupt the balance of gene expression and thereby decrease organismal fitness and viability. Such abnormalities occur in most solid tumors and also cause severe developmental defects and spontaneous abortions. In contrast to the imbalances in...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825453/ https://www.ncbi.nlm.nih.gov/pubmed/35100381 http://dx.doi.org/10.1093/genetics/iyab197 |