Enhancing autophagy maturation with CCZ1-MON1A complex alleviates neuropathology and memory defects in Alzheimer disease models

Rationale: Impairment of autophagy maturation has been implicated in Alzheimer's disease (AD) pathogenesis. However, the mechanism for this impairment has not been elucidated, and whether enhancing autophagy maturation is a viable therapeutic strategy for AD has not been verified. Methods: We e...

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Detalles Bibliográficos
Autores principales: Cai, Cui-Zan, Zhuang, Xu-Xu, Zhu, Qi, Wu, Ming-Yue, Su, Huanxing, Wang, Xiao-jin, Iyaswamy, Ashok, Yue, Zhenyu, Wang, Qian, Zhang, Bin, Xue, Yu, Tan, Jieqiong, Li, Min, He, Huanhuan, Lu, Jia-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825577/
https://www.ncbi.nlm.nih.gov/pubmed/35198070
http://dx.doi.org/10.7150/thno.64148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825577/
https://www.ncbi.nlm.nih.gov/pubmed/35198070
http://dx.doi.org/10.7150/thno.64148

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