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Piezo1-mediated mechanosensation in bone marrow macrophages promotes vascular niche regeneration after irradiation injury

Background: Irradiation disrupts the vascular niche where hematopoietic stem cells (HSCs) reside, causing delayed hematopoietic reconstruction. The subsequent recovery of sinusoidal vessels is key to vascular niche regeneration and a prerequisite for hematopoietic reconstruction. We hypothesize that...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaomei, Hou, Lijia, Li, Fengjie, Zhang, Weiwei, Wu, Chun, Xiang, Lixin, Li, Jiuxuan, Zhou, Luping, Wang, Xiaojie, Xiang, Yang, Xiao, Yanni, Li, Shengwen Calvin, Chen, Li, Ran, Qian, Li, Zhongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825582/
https://www.ncbi.nlm.nih.gov/pubmed/35198061
http://dx.doi.org/10.7150/thno.64963