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Exosome-mediated delivery of RBP-J decoy oligodeoxynucleotides ameliorates hepatic fibrosis in mice

Rationale: Macrophages play multi-dimensional roles in hepatic fibrosis. Studies have implicated Notch signaling mediated by the transcription factor RBP-J in macrophage activation and plasticity. Additionally, we have previously shown that myeloid-specific disruption of RBP-J can ameliorate hepatic...

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Detalles Bibliográficos
Autores principales: He, Fei, Li, Wei-Na, Li, Xin-Xin, Yue, Kang-Yi, Duan, Juan-Li, Ruan, Bai, Liu, Jing-Jing, Song, Ping, Yue, Zhen-Sheng, Tao, Kai-Shan, Wang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825583/
https://www.ncbi.nlm.nih.gov/pubmed/35198075
http://dx.doi.org/10.7150/thno.69885