Gα(12) overexpression in hepatocytes by ER stress exacerbates acute liver injury via ROCK1-mediated miR-15a and ALOX12 dysregulation

Rationale: Liver injury must be further characterized to identify novel therapeutic approaches. Endoplasmic reticulum (ER) stress may cause hepatocyte death. Gα(12) affects cell viability and its expression varies depending on physiological conditions. This study investigated whether hepatocyte-spec...

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Detalles Bibliográficos
Autores principales: Tak, Jihoon, Kim, Yun Seok, Kim, Tae Hyun, Park, Gil-Chun, Hwang, Shin, Kim, Sang Geon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825599/
https://www.ncbi.nlm.nih.gov/pubmed/35198058
http://dx.doi.org/10.7150/thno.67722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825599/
https://www.ncbi.nlm.nih.gov/pubmed/35198058
http://dx.doi.org/10.7150/thno.67722

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