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DNA repair protein DNA-PK protects PC12 cells from oxidative stress-induced apoptosis involving AKT phosphorylation

BACKGROUND: Emerging evidence suggest that DNA-PK complex plays a role in the cellular response to oxidative stress, in addition to its function of double strand break (DSB) repair. In this study we evaluated whether DNA-PK participates in oxidative stress response and whether this role is independe...

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Detalles Bibliográficos
Autores principales: Cardinale, Alessio, Saladini, Serena, Lupacchini, Leonardo, Ruspantini, Irene, De Dominicis, Chiara, Papale, Marco, Silvagno, Francesca, Garaci, Enrico, Mollinari, Cristiana, Merlo, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825611/
https://www.ncbi.nlm.nih.gov/pubmed/34797489
http://dx.doi.org/10.1007/s11033-021-06934-5