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Alterations in calmodulin-cardiac ryanodine receptor molecular recognition in congenital arrhythmias
Calmodulin (CaM), a ubiquitous and highly conserved Ca(2+)-sensor protein involved in the regulation of over 300 molecular targets, has been recently associated with severe forms of lethal arrhythmia. Here, we investigated how arrhythmia-associated mutations in CaM localized at the C-terminal lobe a...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825638/ https://www.ncbi.nlm.nih.gov/pubmed/35133504 http://dx.doi.org/10.1007/s00018-022-04165-w |