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Generation of ENSEMBL-based proteogenomics databases boosts the identification of non-canonical peptides

SUMMARY: We have implemented the pypgatk package and the pgdb workflow to create proteogenomics databases based on ENSEMBL resources. The tools allow the generation of protein sequences from novel protein-coding transcripts by performing a three-frame translation of pseudogenes, lncRNAs and other no...

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Detalles Bibliográficos
Autores principales: Umer, Husen M, Audain, Enrique, Zhu, Yafeng, Pfeuffer, Julianus, Sachsenberg, Timo, Lehtiö, Janne, Branca, Rui M, Perez-Riverol, Yasset
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825679/
https://www.ncbi.nlm.nih.gov/pubmed/34904638
http://dx.doi.org/10.1093/bioinformatics/btab838