An extended motif in the SARS-CoV-2 spike modulates binding and release of host coatomer in retrograde trafficking

β-Coronaviruses such as SARS-CoV-2 hijack coatomer protein-I (COPI) for spike protein retrograde trafficking to the progeny assembly site in endoplasmic reticulum-Golgi intermediate compartment (ERGIC). However, limited residue-level details are available into how the spike interacts with COPI. Here...

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Detalles Bibliográficos
Autores principales: Dey, Debajit, Singh, Suruchi, Khan, Saif, Martin, Matthew, Schnicker, Nicholas J., Gakhar, Lokesh, Pierce, Brian G., Hasan, S. Saif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825798/
https://www.ncbi.nlm.nih.gov/pubmed/35136165
http://dx.doi.org/10.1038/s42003-022-03063-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825798/
https://www.ncbi.nlm.nih.gov/pubmed/35136165
http://dx.doi.org/10.1038/s42003-022-03063-y

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