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Dramatic Therapeutic Response to Dabrafenib Plus Trametinib in BRAF V600E Mutated Papillary Craniopharyngiomas: A Case Report and Literature Review

BACKGROUND: Craniopharyngioma is a rare intracranial tumor, with a high morbidity rate due to its common refractiveness to conventional treatments. BRAF V600E mutation has recently been identified as the principal oncogenic molecular driver of papillary craniopharyngiomas (PCP), one of the two main...

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Detalles Bibliográficos
Autores principales: Fasano, Morena, Della Corte, Carminia Maria, Caterino, Marianna, Pirozzi, Mario, Rauso, Raffaele, Troiani, Teresa, Martini, Giulia, Napolitano, Stefania, Morgillo, Floriana, Ciardiello, Fortunato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825802/
https://www.ncbi.nlm.nih.gov/pubmed/35155453
http://dx.doi.org/10.3389/fmed.2021.652005