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MST1 deletion protects β-cells in a mouse model of diabetes

The pro-apoptotic kinase Mammalian Sterile 20-like kinase 1 (MST1), an integral component of the Hippo pathway, is a key regulator of organ size, stress response, and tissue homeostasis; its aberrant hyperactivation is linked to multiple pathological disorders including diabetes. Here we show that M...

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Detalles Bibliográficos
Autores principales: Ardestani, Amin, Maedler, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825818/
https://www.ncbi.nlm.nih.gov/pubmed/35136036
http://dx.doi.org/10.1038/s41387-022-00186-3