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RCSB Protein Data Bank: improved annotation, search and visualization of membrane protein structures archived in the PDB

MOTIVATION: Membrane proteins are encoded by approximately one fifth of human genes but account for more than half of all US FDA approved drug targets. Thanks to new technological advances, the number of membrane proteins archived in the PDB is growing rapidly. However, automatic identification of m...

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Detalles Bibliográficos
Autores principales: Bittrich, Sebastian, Rose, Yana, Segura, Joan, Lowe, Robert, Westbrook, John D, Duarte, Jose M, Burley, Stephen K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826025/
https://www.ncbi.nlm.nih.gov/pubmed/34864908
http://dx.doi.org/10.1093/bioinformatics/btab813