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Cannabidiol Increases Seizure Resistance and Improves Behavior in an Scn8a Mouse Model

Voltage-gated sodium channel genes are an important family of human epilepsy genes. De novo missense mutations in SCN8A (encoding Na(v)1.6) are associated with a spectrum of clinical presentation, including multiple seizure types, movement disorders, intellectual disability, and behavioral abnormali...

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Detalles Bibliográficos
Autores principales: Shapiro, Lindsey, Escayg, Andrew, Wong, Jennifer C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826257/
https://www.ncbi.nlm.nih.gov/pubmed/35153788
http://dx.doi.org/10.3389/fphar.2022.815950