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Cannabidiol Increases Seizure Resistance and Improves Behavior in an Scn8a Mouse Model
Voltage-gated sodium channel genes are an important family of human epilepsy genes. De novo missense mutations in SCN8A (encoding Na(v)1.6) are associated with a spectrum of clinical presentation, including multiple seizure types, movement disorders, intellectual disability, and behavioral abnormali...
Autores principales: | Shapiro, Lindsey, Escayg, Andrew, Wong, Jennifer C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826257/ https://www.ncbi.nlm.nih.gov/pubmed/35153788 http://dx.doi.org/10.3389/fphar.2022.815950 |
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