Mechanisms underlying TARP modulation of the GluA1/2-γ8 AMPA receptor

AMPA-type glutamate receptors (AMPARs) mediate rapid signal transmission at excitatory synapses in the brain. Glutamate binding to the receptor’s ligand-binding domains (LBDs) leads to ion channel activation and desensitization. Gating kinetics shape synaptic transmission and are strongly modulated...

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Detalles Bibliográficos
Autores principales: Herguedas, Beatriz, Kohegyi, Bianka K., Dohrke, Jan-Niklas, Watson, Jake F., Zhang, Danyang, Ho, Hinze, Shaikh, Saher A., Lape, Remigijus, Krieger, James M., Greger, Ingo H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826358/
https://www.ncbi.nlm.nih.gov/pubmed/35136046
http://dx.doi.org/10.1038/s41467-022-28404-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826358/
https://www.ncbi.nlm.nih.gov/pubmed/35136046
http://dx.doi.org/10.1038/s41467-022-28404-7

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