Cargando…

MYC-activated RNA N6-methyladenosine reader IGF2BP3 promotes cell proliferation and metastasis in nasopharyngeal carcinoma

N6-Methyladenosine (m6A) modification is the most abundant RNA modification in eukaryotic cells. IGF2BP3, a well-known m6A reader, is deregulated in many cancers, but its role in nasopharyngeal carcinoma (NPC) remains unclear. In this work, IGF2BP3 was upregulated in NPC tissues and cells. The high...

Descripción completa

Detalles Bibliográficos
Autores principales: Du, Mingyu, Peng, Yi, Li, Yang, Sun, Wenyue, Zhu, Huanfeng, Wu, Jing, Zong, Dan, Wu, Lirong, He, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826370/
https://www.ncbi.nlm.nih.gov/pubmed/35136045
http://dx.doi.org/10.1038/s41420-022-00844-6