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Citrullination Was Introduced into Animals by Horizontal Gene Transfer from Cyanobacteria

Protein posttranslational modifications add great sophistication to biological systems. Citrullination, a key regulatory mechanism in human physiology and pathophysiology, is enigmatic from an evolutionary perspective. Although the citrullinating enzymes peptidylarginine deiminases (PADIs) are ubiqu...

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Detalles Bibliográficos
Autores principales: Cummings, Thomas F M, Gori, Kevin, Sanchez-Pulido, Luis, Gavriilidis, Gavriil, Moi, David, Wilson, Abigail R, Murchison, Elizabeth, Dessimoz, Christophe, Ponting, Chris P, Christophorou, Maria A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826395/
https://www.ncbi.nlm.nih.gov/pubmed/34730808
http://dx.doi.org/10.1093/molbev/msab317