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p38 activation occurs mainly in microglia in the P301S Tauopathy mouse model

Tauopathies are a group of neurodegenerative diseases characterized by the accumulation of hyperphosphorylated tau protein in the brain. Many of these pathologies also present an inflammatory component determined by the activation of microglia, the resident immune cells of the brain. p38 MAPK is one...

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Detalles Bibliográficos
Autores principales: Perea, Juan R., García, Esther, Vallés-Saiz, Laura, Cuadros, Raquel, Hernández, Félix, Bolós, Marta, Avila, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826411/
https://www.ncbi.nlm.nih.gov/pubmed/35136118
http://dx.doi.org/10.1038/s41598-022-05980-8