Accurate MHC Motif Deconvolution of Immunopeptidomics Data Reveals a Significant Contribution of DRB3, 4 and 5 to the Total DR Immunopeptidome

Mass spectrometry (MS) based immunopeptidomics is used in several biomedical applications including neo-epitope discovery in oncology, next-generation vaccine development and protein-drug immunogenicity assessment. Immunopeptidome data are highly complex given the expression of multiple HLA alleles...

Descripción completa

Detalles Bibliográficos
Autores principales: Kaabinejadian, Saghar, Barra, Carolina, Alvarez, Bruno, Yari, Hooman, Hildebrand, William H., Nielsen, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826445/
https://www.ncbi.nlm.nih.gov/pubmed/35154160
http://dx.doi.org/10.3389/fimmu.2022.835454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826445/
https://www.ncbi.nlm.nih.gov/pubmed/35154160
http://dx.doi.org/10.3389/fimmu.2022.835454

Ejemplares similares