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Accurate MHC Motif Deconvolution of Immunopeptidomics Data Reveals a Significant Contribution of DRB3, 4 and 5 to the Total DR Immunopeptidome

Mass spectrometry (MS) based immunopeptidomics is used in several biomedical applications including neo-epitope discovery in oncology, next-generation vaccine development and protein-drug immunogenicity assessment. Immunopeptidome data are highly complex given the expression of multiple HLA alleles...

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Detalles Bibliográficos
Autores principales:	Kaabinejadian, Saghar, Barra, Carolina, Alvarez, Bruno, Yari, Hooman, Hildebrand, William H., Nielsen, Morten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826445/ https://www.ncbi.nlm.nih.gov/pubmed/35154160 http://dx.doi.org/10.3389/fimmu.2022.835454

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