Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry

Tousled-like kinases (TLKs) are nuclear serine-threonine kinases essential for genome maintenance and proper cell division in animals and plants. A major function of TLKs is to phosphorylate the histone chaperone proteins ASF1a and ASF1b to facilitate DNA replication-coupled nucleosome assembly, but...

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Detalles Bibliográficos
Autores principales: Simon, Bertrand, Lou, Hua Jane, Huet-Calderwood, Clotilde, Shi, Guangda, Boggon, Titus J., Turk, Benjamin E., Calderwood, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826447/
https://www.ncbi.nlm.nih.gov/pubmed/35136069
http://dx.doi.org/10.1038/s41467-022-28427-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826447/
https://www.ncbi.nlm.nih.gov/pubmed/35136069
http://dx.doi.org/10.1038/s41467-022-28427-0

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