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Inducible Slc4a11 Knockout Triggers Corneal Edema Through Perturbation of Corneal Endothelial Pump

PURPOSE: The conventional Slc4a11 knockout (KO) shows significant corneal edema at eye opening, a fact that complicates the study of the initial events leading to edema. An inducible KO would provide opportunities to examine early events following loss of Slc4a11 activity. METHODS: Slc4a11 Flox (SF)...

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Detalles Bibliográficos
Autores principales: Ogando, Diego G., Shyam, Rajalekshmy, Kim, Edward T., Wang, Yen-Chiao, Liu, Chia-Yang, Bonanno, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826551/
https://www.ncbi.nlm.nih.gov/pubmed/34190974
http://dx.doi.org/10.1167/iovs.62.7.28