Human embryonic genome activation initiates at the one-cell stage

In human embryos, the initiation of transcription (embryonic genome activation [EGA]) occurs by the eight-cell stage, but its exact timing and profile are unclear. To address this, we profiled gene expression at depth in human metaphase II oocytes and bipronuclear (2PN) one-cell embryos. High-resolu...

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Detalles Bibliográficos
Autores principales: Asami, Maki, Lam, Brian Y.H., Ma, Marcella K., Rainbow, Kara, Braun, Stefanie, VerMilyea, Matthew D., Yeo, Giles S.H., Perry, Anthony C.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826644/
https://www.ncbi.nlm.nih.gov/pubmed/34936886
http://dx.doi.org/10.1016/j.stem.2021.11.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826644/
https://www.ncbi.nlm.nih.gov/pubmed/34936886
http://dx.doi.org/10.1016/j.stem.2021.11.012

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