BRD4 Inhibition Attenuates Inflammatory Pain by Ameliorating NLRP3 Inflammasome-Induced Pyroptosis

Chronic pain, such as persistent inflammatory pain, remains a public health problem that has no effective treatment at present. Bromodomain-containing protein 4 (BRD4) inhibition, induced by JQ1 injection or BRD4 knockdown, has been used to attenuate inflammatory pain; However, it remains elusive wh...

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Detalles Bibliográficos
Autores principales: Hua, Tong, Wang, Haowei, Fan, Xiaoyi, An, Ni, Li, Jian, Song, Honghao, Kong, Erliang, Li, Yongchang, Yuan, Hongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826720/
https://www.ncbi.nlm.nih.gov/pubmed/35154163
http://dx.doi.org/10.3389/fimmu.2022.837977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826720/
https://www.ncbi.nlm.nih.gov/pubmed/35154163
http://dx.doi.org/10.3389/fimmu.2022.837977

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