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Transcriptome-Wide Identification of Coding and Noncoding RNA-Binding Proteins Defines the Comprehensive RNA Interactome of Leishmania mexicana

Proteomic profiling of RNA-binding proteins in Leishmania is currently limited to polyadenylated mRNA-binding proteins, leaving proteins that interact with nonadenylated RNAs, including noncoding RNAs and pre-mRNAs, unidentified. Using a combination of unbiased orthogonal organic phase separation me...

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Detalles Bibliográficos
Autores principales: Kalesh, Karunakaran, Wei, Wenbin, Mantilla, Brian S., Roumeliotis, Theodoros I., Choudhary, Jyoti, Denny, Paul W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826732/
https://www.ncbi.nlm.nih.gov/pubmed/35138191
http://dx.doi.org/10.1128/spectrum.02422-21