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Application of Amplicon-Based Targeted NGS Technology for Diagnosis of Drug-Resistant Tuberculosis Using FFPE Specimens

Next-generation sequencing (NGS) enables rapid identification of common and rare drug-resistant genetic variations from tuberculosis (TB) patients’ sputum samples and MTB isolates. However, whether this technology is effective for formalin-fixed and paraffin-embedded (FFPE) tissues remains unclear....

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Detalles Bibliográficos
Autores principales: Song, Jing, Du, Weili, Liu, Zichen, Che, Jialu, Li, Kun, Che, Nanying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826733/
https://www.ncbi.nlm.nih.gov/pubmed/35138166
http://dx.doi.org/10.1128/spectrum.01358-21