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Targeting Amyloids with [(18)F]AV-45 for Medullary Thyroid Carcinoma Positron Emission Tomography/Computed Tomography Imaging: A Pilot Clinical Study

[Image: see text] Medullary thyroid carcinoma (MTC) is a malignant neuroendocrine tumor with a high recurrence rate. Amyloid plaques formed from the misfolding of calcitonin are the key characteristics of MTC. Herein, we conducted a first-in-human pilot clinical study by applying a β-amyloid-specifi...

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Detalles Bibliográficos
Autores principales: Li, Chun, Zhang, Pengxin, Nie, Ruirui, Gong, Xiaoyan, Xie, Jinghui, Yu, Zilin, Wang, Chengdong, Zhang, Hua, Yan, Ran, Lu, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826757/
https://www.ncbi.nlm.nih.gov/pubmed/34982563
http://dx.doi.org/10.1021/acs.molpharmaceut.1c00680