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Hydrogen bond activated glycosylation under mild conditions

Herein, we report a new glycosylation system for the highly efficient and stereoselective formation of glycosidic bonds using glycosyl N-phenyl trifluoroacetimidate (PTFAI) donors and a charged thiourea hydrogen-bond-donor catalyst. The glycosylation protocol features broad substrate scope, controll...

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Detalles Bibliográficos
Autores principales: Xiao, Ke, Hu, Yongxin, Wan, Yongyong, Li, XinXin, Nie, Qin, Yan, Hao, Wang, Liming, Liao, Jinxi, Liu, Deyong, Tu, Yuanhong, Sun, Jiansong, Codée, Jeroen D. C., Zhang, Qingju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826775/
https://www.ncbi.nlm.nih.gov/pubmed/35282639
http://dx.doi.org/10.1039/d1sc05772c