Novel Humanized Peripheral Blood Mononuclear Cell Mouse Model with Delayed Onset of Graft-versus-Host Disease for Preclinical HIV Research

Humanized mouse models are based on the engraftment of human cells in immunodeficient mouse strains, most notably the NSG strain. Most used models have a major limitation in common, the development of graft-versus-host disease (GVHD). GVHD not only introduces variabilities into the research data but...

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Detalles Bibliográficos
Autores principales: Holguin, Leo, Echavarria, Liliana, Burnett, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Pathogenesis and Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826814/
https://www.ncbi.nlm.nih.gov/pubmed/34818071
http://dx.doi.org/10.1128/JVI.01394-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826814/
https://www.ncbi.nlm.nih.gov/pubmed/34818071
http://dx.doi.org/10.1128/JVI.01394-21

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