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Inactivation of the Response Regulator AgrA Has a Pleiotropic Effect on Biofilm Formation, Pathogenesis and Stress Response in Staphylococcus lugdunensis

Staphylococcus lugdunensis is a coagulase-negative Staphylococcus that emerges as an important opportunistic pathogen. However, little is known about the regulation underlying the transition from commensal to virulent state. Based on knowledge of S. aureus virulence, we suspected that the agr quorum...

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Detalles Bibliográficos
Autores principales: Aubourg, Marion, Pottier, Marine, Léon, Albertine, Bernay, Benoit, Dhalluin, Anne, Cacaci, Margherita, Torelli, Riccardo, Ledormand, Pierre, Martini, Cecilia, Sanguinetti, Maurizio, Auzou, Michel, Gravey, François, Giard, Jean-Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826819/
https://www.ncbi.nlm.nih.gov/pubmed/35138170
http://dx.doi.org/10.1128/spectrum.01598-21