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Avian Hepatitis E Virus ORF2 Protein Interacts with Rap1b to Induce Cytoskeleton Rearrangement That Facilitates Virus Internalization

Avian hepatitis E virus (HEV) causes liver diseases and multiple extrahepatic disorders in chickens. However, the mechanisms involved in avian HEV entry remain elusive. Herein, we identified the RAS-related protein 1b (Rap1b) as a potential HEV-ORF2 protein interacting candidate. Experimental infect...

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Detalles Bibliográficos
Autores principales: Zhang, Beibei, Fan, Mengnan, Fan, Jie, Luo, Yuhang, Wang, Jie, Wang, Yajing, Liu, Baoyuan, Sun, Yani, Zhao, Qin, Hiscox, Julian A., Nan, Yuchen, Zhou, En-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826821/
https://www.ncbi.nlm.nih.gov/pubmed/35138149
http://dx.doi.org/10.1128/spectrum.02265-21