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PPE51 mediates uptake of trehalose across the mycomembrane of Mycobacterium tuberculosis

The disaccharide trehalose is essential for viability of Mycobacterium tuberculosis, which synthesizes trehalose de novo but can also utilize exogenous trehalose. The mycobacterial cell wall encompasses two permeability barriers, the cytoplasmic membrane and the outer mycolic acid-containing mycomem...

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Detalles Bibliográficos
Autores principales: Babu Sait, Mohammed Rizwan, Koliwer-Brandl, Hendrik, Stewart, Jessica A., Swarts, Benjamin M., Jacobsen, Marc, Ioerger, Thomas R., Kalscheuer, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826857/
https://www.ncbi.nlm.nih.gov/pubmed/35136132
http://dx.doi.org/10.1038/s41598-022-06109-7