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The Combined Expression of the Nonstructural Protein NS1 and the N-Terminal Half of NS2 (NS2(1-180)) by ChAdOx1 and MVA Confers Protection against Clinical Disease in Sheep upon Bluetongue Virus Challenge

Bluetongue, caused by bluetongue virus (BTV), is a widespread arthropod-borne disease of ruminants that entails a recurrent threat to the primary sector of developed and developing countries. In this work, we report modified vaccinia virus Ankara (MVA) and ChAdOx1-vectored vaccines designed to simul...

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Detalles Bibliográficos
Autores principales: Utrilla-Trigo, Sergio, Jiménez-Cabello, Luis, Calvo-Pinilla, Eva, Marín-López, Alejandro, Lorenzo, Gema, Sánchez-Cordón, Pedro, Moreno, Sandra, Benavides, Julio, Gilbert, Sarah, Nogales, Aitor, Ortego, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826911/
https://www.ncbi.nlm.nih.gov/pubmed/34787454
http://dx.doi.org/10.1128/JVI.01614-21