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The Combined Expression of the Nonstructural Protein NS1 and the N-Terminal Half of NS2 (NS2(1-180)) by ChAdOx1 and MVA Confers Protection against Clinical Disease in Sheep upon Bluetongue Virus Challenge
Bluetongue, caused by bluetongue virus (BTV), is a widespread arthropod-borne disease of ruminants that entails a recurrent threat to the primary sector of developed and developing countries. In this work, we report modified vaccinia virus Ankara (MVA) and ChAdOx1-vectored vaccines designed to simul...
Autores principales: | Utrilla-Trigo, Sergio, Jiménez-Cabello, Luis, Calvo-Pinilla, Eva, Marín-López, Alejandro, Lorenzo, Gema, Sánchez-Cordón, Pedro, Moreno, Sandra, Benavides, Julio, Gilbert, Sarah, Nogales, Aitor, Ortego, Javier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826911/ https://www.ncbi.nlm.nih.gov/pubmed/34787454 http://dx.doi.org/10.1128/JVI.01614-21 |
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